Distant Metastasis Risk Definition by Tumor Biomarkers Integrated Nomogram Approach for Locally Advanced Nasopharyngeal Carcinoma
نویسندگان
چکیده
منابع مشابه
Molecular Prognostic Prediction for Locally Advanced Nasopharyngeal Carcinoma by Support Vector Machine Integrated Approach
BACKGROUND Accurate prognostication of locally advanced nasopharyngeal carcinoma (NPC) will benefit patients for tailored therapy. Here, we addressed this issue by developing a mathematical algorithm based on support vector machine (SVM) through integrating the expression levels of multi-biomarkers. METHODOLOGY/PRINCIPAL FINDINGS Ninety-seven locally advanced NPC patients in a randomized cont...
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Positron emission tomography (PET) using fluorine-18-labeled fluorodeoxyglucose (18F-FDG) which is a promising method for the early detection of DM of NPC [7] was not mentioned in this case report, although early detection of further liver metastasis might not have changed the clinical practice nor improved patient’s survival [8]. It would be interesting to know the intensity of fixation in PET...
متن کاملUse of pretreatment serum uric acid level to predict metastasis in locally advanced nasopharyngeal carcinoma.
BACKGROUND The purpose of this study was to determine the predictive value of pretreatment serum uric acid (SUA) for metastasis in locally advanced nasopharyngeal carcinoma (NPC) treated with intensity-modulated radiotherapy. METHODS This retrospective study examined 1063 patients with locally advanced NPC. Multivariate survival analysis was used. RESULTS High pretreatment SUA level (>353.4...
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PURPOSE Despite significant improvement in locoregional control in the contemporary era of nasopharyngeal carcinoma (NPC) treatment, patients still suffer from a significant risk of distant metastasis (DM). Identifying those patients at risk of DM would aid in personalized treatment in the future. MicroRNAs (miRNAs) play many important roles in human cancers; hence, we proceeded to address the ...
متن کاملConcurrent chemoradiotherapy in locally and/or regionally advanced nasopharyngeal carcinoma.
The aim of the study was to investigate the efficacy of concurrent chemoradiotherapy (CCRT) in patients with locally and/or regionally advanced nasopharyngeal carcinoma (NPC). Between February 2005 and November 2007, 27 patients with advanced NPC were included in a prospective study of CCRT at the Radiotherapy and Oncology Institute in Skopje. Radiotherapy was performed using a sophisticated th...
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ژورنال
عنوان ژورنال: Cancer Control
سال: 2019
ISSN: 1073-2748,1073-2748
DOI: 10.1177/1073274819883895